F7 / Factor VII Monoclonal Antibody LS-C188524 from LSBio

Product Specs
ItemF7 / Factor VII Monoclonal Antibody
CompanyLSBio
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberLS-C188524
ApplicationsELISA, RIA, WB
Conjugate/TagUnconjugated
FormatPBS, 0.09% sodium azide
PurityProtein G purified
ReactivityHuman
TargetF7 / Factor VII
IsotypeIgG1
CloneRFF-VII/1
HostMouse
NCBI Full Gene Namecoagulation factor VII
ClonalityMonoclonal
NCBI Gene AliasesSPCA
Quantity0.5 mg

Specifications/Features

Specificity: Recognizes Factor VII, a serine protease found circulating in the blood. It initiates the extrinsic pathway of blood coagulation in conjunction with tissue factor. Tissue factor is found on the outside of blood vessels. When the vessels is damaged, tissue factor is exposed to the blood and circulating Factor VII. Once bound to tissue factor, Factor VII is activated by different proteases and converts Factor IX to IXa. Factor VII deficiency is a rare hereditary hemorrhagic disease. Symptoms range from mild to severe. Clone RFF-VII/1 is a strong inhibitor of Factor VII activity. It may be used to detect Factor VII in immunoassays in combination with clone RFF-VII/2 as a capture reagent

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